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Chlamydophila pecorum: Typing

Jones et al., (1997) have described subtypes of C. pecorum have been described which vary in their ability to cause disease.  Rodolakis et al., (1989) reported that C. pecorum isolated from the faeces of sheep were antigenically heterogeneous. Variations in the major outer membrane protein (MOMP) of C. pecorum strains from various conditions have been observed by immunoblotting (Fukushi and Hirai, 1992).  However C. pecorum strains from several different immunotypes have been shown to possess identical MOMP sequences (Kaltenboeck et al., 1993). A key challenge is to identify for C. pecorum strains the relationships between immunotype, MOMP sequence, biological variation, host tropism  and disease (Anderson et al., 1996). 

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