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Web resources of chlamydial interest

Please note: www.chlamydiae.com has no control of the changing content of sites to which it links. The existence of a link from this site does not imply endorsement of that site. This page being updated Jan 2008.

Chlamydial Genomics and proteomics

  Stanford / Berkely Chlamydia genomics project C. trachomatis D & L2; C. pneumoniae CWL 029 [C. trachomatis serovar D was the first chlamydial genomic sequence in a project shared between Berkeley (Richard Stephen's group) and Stanford (Ron Davies group). The original Berkeley site has disappeared and this site was last updated in 1999 and has been surpassed by other genomics sites. However this was an historic collaboration, making high quality genomic data available to the research community as it happened. Anybody who provides quality whole genome sequence data for the very first time deserves 3 star rating]. Accessed 2/1/2008

Site resides within the UK Chlamydia trachomatis serovar A. Sanger Institute 1.052Mb; C. trachomatis Serovar B [Latest sequences. Databases available but finishing still in progress, publication pending]. Accessed 2/1/2008

Site resides within the UK Chlamydia trachomatis Jali (Gambia) Serovar B 1.04 Mb [Latest sequences. Database available but finishing still in progress, publication pending]. Accessed 2/1/2008

Site resides within the UK Chlamydia trachomatis serovar L2 1.038 MB [Latest sequences. Database available but finishing and gene prediction still in progress, publication pending] Accessed 2/1/2008

 C. muridarum (Nigg strain) Accessed 2/1/2008  

Site resides within the UK Chlamydophila abortus genome S26/3 Wellcome Trust Sanger Institute and Moredun Institute. Associated publication  [961 predicted coding sequences, 842 conserved in other Chlamydophila; no toxin genes; no genes for tryptophan metabolism or nucleotide salvage]. Accessed 2/1/2008

   Chlamydophila caviae (former GPIC strain) [Posted by TIGR 5/8/2003]

Site resides elsewhere on the Internet Chlamydophila felis genome strain Fe/C-56 [Sequenced at Kitasato University Japan a long time ago but not completely annotated. Available via Genbank FTP at link given]. Accessed 2/1/2008

   Chlamydophila pneumoniae AR39 TIGR  Accessed 2/1/2008

  Chlamydophila pneumoniae CWL029 Berkeley & Stanford Accessed 2/1/2008

Site resides elsewhere on the Internet Chlamydophila pneumoniae genome J138: Yamaguchi and Kyushu Universities, Japan Also Genbank Accessed 2/1/2008

Site resides within Europe Environmental Chlamydia genome project, Technical University of Munich and the University of Vienna. [Mathias Horn's group provided the first genomic sequence for an environmental chlamydiales species, Protochlamydia amoebophila UWE25]. Accessed 2/1/2008

Site resides elsewhere on the Internet Simkania negevensis Z genome. Being sequenced by TIGR. Sequence data still incomplete at 2/1/2008

  STD Genome database also at NMPDR [Funding of the excellent STDGEN NIAID/NIH website finished in 2004. A real pity because there were excellent tools available. Limited functionality still available at the alternate link provided]. Accessed 2/1/2008

Site resides within Europe EMBL Bioinformatics proteomics database [Select appropriate database from left hand frame] Accessed 2/1/2008

Site resides within Europe Chlamydial proteomics database University of Aarhus, Denmark [Includes 2D PAGE database of C. pneumoniae VR1310 proteome and IFN-gamma induced HeLa cell proteins] Accessed 2/1/2008


Molecular Biology (General & Bioinformatics)

   Bacterial Ribosome Database : 16S ribosomal RNA sequences etc Accessed Release 9.56 2/1/2008
Site resides elsewhere on the Internet
Bioweb software tools: Useful sequence-related, on-line software tools Accessed 2/1/2008
   Biotech : Educational resource in biotechnology, Glossary
   Brookhaven : Classic Protein structure and crystallography database. Accessed 3/1/2008
Site resides within the UK Cell signalling gateway AfCS Nature Database of proteins and results relevant to eukaryotic cell signalling Accessed 3/1/2008
Site resides elsewhere on the Internet DNA Vaccines  and gene therapy (Genovac) Accessed 3/1/2008
Site resides within the UK EBI : EMBL. UK site for gene databases and for molecular biology programs Accessed 3/1/2008
Site resides elsewhere on the Internet ExPASy : Swiss Institute of Bioinformatics. Important proteomics  site. Accessed 3/1/2008 
Site resides within Europe LITBIO Networked Bioinformatics Resources Accessed 3/1/2008 
Site resides elsewhere on the Internet Molecular Biology gateway (Horizon Press). Links to companies, protocols etc Accessed 3/1/2008 
Site resides within the UK MEROPS : Sanger Institute eptidase data base. Accessed 3/1/2008
   Molecular and Cell Biology, Immunology etc Protocols Laboratory protocols Accessed 3/1/2008
Site resides within the UK Wellcome-Sanger Institute : Hinxton, Cambridge. Genome sequencing projects. Accessed 3/1/2008
   National Center for Biotechnology information : Excellent site. Blast, Entrez, PubMed searches etc Accessed 3/1/2008
Site resides within the UK PDBsum : Protein databank summary, European Bioinformatics Institute, London Accessed 3/1/2008
Site resides within the UK Pfam : Protein sequence alignments and domains. At Sanger Institute but no longer supported beyond release 23.0 Accessed 3/1/2008
Site resides within the UK Promega web site: Southampton based, with post grad student forum & jobs Accessed 3/1/2008
Site resides within the UK Protein topology : Protein topology home page Accessed 3/1/2008
   PROW : Protein Reviews on the Web: Sequences and nomenclature of CD domains in immunology Accessed 3/1/2008
Site resides within the UK SCOP : Structural classification of proteins Accessed 3/1/2008 
   SDSC Biology workbench Protein and nucleic acid search tools of San Diego Supercomputer Center Accessed 3/1/2008
   TIGR : Comprehensive microbial resource Accessed 3/1/2008
Site resides within Europe TMAP : Membrane protein structural predictions Accessed 3/1/2008
    Protein Lounge : Human transcription factors and siRNA database Accessed 3/1/2008
Site resides within the UK  Transcription factor prediction database Accessed 3/1/2008
Site resides elsewhere on the Internet WIT : Superseded by The Seed and Puma 2. Gene function. Metabolic pathways. Accessed 3/1/2008


Science dictionaries and general reference

    Biotech life sciences dictionary [About 8,500 words] Accessed 3/1/2008

Site resides within the UK On Line Medical Dictionary Accessed 3/1/2008


Clinical information and resources on chlamydiae

   American Medical Association Womens Health Information [Women's health issues including Chlamydia]

   AVMA Compendium on measures to control C. psittaci infections in birds and humans 2002 [National association of state public health veterinarians]

Site resides within the UK BMA Board of Science and Education report on sexually transmitted diseases in the UK, February 2002 Full document (776 Kb) [Acrobat] 

Site resides within Europe European STI Management Guidelines [Published in International Journal of STD and AIDS 12, Supplement 3, October 2001]. 

Site resides within the UK International Journal of STD and AIDS. [Joint publication of IUSTI and AGUM - see below. Requires personal or institutional subscription to access the on-line version].

Site resides within Europe Journal of the European Academy of Dermatology and Venerology. [In most of Europe dermatology and venerology are combined disciplines. This is the official Journal of the EADV. Heavily dominated by dermatology limiting its usefulness to people interested primarily in STIs].

Site resides within the UK National strategy for sexual health and HIV [UK Department of Health]. Full document  [Acrobat] 

Site resides elsewhere on the Internet Sexually transmitted diseases. Journal of the American Sexually transmitted diseases association. [Editor is Julius Schachter, a prominent chlamydiologist. Full on-line access requires a subscription].

Site resides within the UK Sexually transmitted infections. [The on-line version of the journal of the same name. Published on behalf of the BASSH. One of the key journals but full access to papers requires an individual or institutional subscription].

Site resides within the UK UK National screening and testing guidelines for sexually transmitted infections. STI 82, Supplement 4 Dec 2006   [FOC registration required]

Site resides within the UK UK PHLS Guidelines for managing outbreaks of sexually transmitted infections, July 2002  [Acrobat]

   US CDC Guidelines on screening tests to detect C. trachomatis and N. gonorrhoeae. October 2002 [Acrobat]

   US patent office searches [For chlamydia related patents use Multi-Find on post log in home page].

   US STD Treatment guidelines, 1998   CDC Atlanta [For clinicians, superseded by guidelines below

   US STD Treatment guidelines, May 2002 CDC Atlanta [For clinicians]   [Acrobat]

   Webcast: CDC guidelines on preventing consequences of STIs 

   US STD Prevalence Report 2000  CDC Atlanta [Acrobat]


Relevant societies

Site resides within the UK  AGUM. The association for Genito Urinary Medicine. [A specialist society providing advice and support for doctors practising genito urinary medicine in the UK. Joint publisher with IUSTI of the International Journal of STD and AIDS. AGUM and MSSVD are currently in merger negotiations].

Site resides elsewhere on the Internet Chlamydia basic research society. [A forum for the presentation and discussion of research on the basic biology and pathogenesis of diseases caused by chlamydiae. Primary activity is a biennial conference. A major goal is to encourage newer people in the field].

Site resides elsewhere on the Internet ISSTDR The International Society for Sexually transmitted disease research. [The foremost society for sexually transmitted disease research, membership is via attendance at one of its conferences. This link gives information about the next conference, to be held in Canada].

Site resides elsewhere on the Internet  IUSTI. International Union against sexually transmitted infections. [Founded in 1923 to promote international cooperation against sexually transmitted diseases. There are active regional branches, eg for Europe, Asia Pacific etc. The web site mainly has information about the various IUSTI conferences and committees].

Site resides within the UK  MSSVD. Medical Society for the Study of Venereally Transmitted Diseases. [Despite its old fashioned name, the UK based MSSVD, is one of the foremost and most active academic societies for studying sexually transmitted infections. The web site has some useful guidelines for people starting in genito-urinary medicine, please details of courses and of meetings of the various groups of the society. The society publishes the key journal Sexually transmitted infections].


Evidence based medicine sources on chlamydial-related problems

Site resides elsewhere on the Internet Bandolier on Chlamydia  [Evidence based medicine study on cost effectiveness of screening]

Chlamydia related reports in the Cochrane Collaboration Library (abstracts)

[Updates of these abstracts may be found by searching on update software's web site, Oxford, UK]

Antibiotic prophylaxis for intrauterine contraceptive device insertion

Antibiotic regimens for endometritis after delivery

Antibiotic for acute bronchitis

Antibiotics in acute asthma

Antibiotics for pre-term premature rupture of membranes

Antibiotics for trachoma

Interventions for encouraging sexual lifestyles and behaviours intended to prevent cervical cancer

Interventions for treating bacterial vaginosis in pregnancy

Interventions for treating genital Chlamydia trachomatis infection in pregnancy

Interventions for treating gonorrhoea in pregnancy

Macrolides for chronic asthma

Multiple risk factor interventions for primary prevention of coronary heart disease

Nonoxynol 9 for preventing vaginal acquisition of sexually transmitted infections by women from men

Population-based interventions for reducing sexually transmitted infections including HIV

Strategies for partner notification for sexually transmitted diseases

For students

   Chlamydia lecture, Wisconsin  University of Wisconsin. [For students. Wisconsin Microbiologists are to be congratulated in making their educational material freely available on the internet. Needs updating]

   Chlamydia chapter in textbook   Becker [Students might find this useful, but out of date]

Site resides within the UK Molecular Biology Notebook. An on line molecular biology course.

 

[MEW]  August., 2003


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